In the premiere of an eight-part documentary series following the staff and patients at New York-Presbyterian Hospital, Dr. Mehmet Oz arranges a reunion between a patient and his ex-wife. Meanwhile, a woman with a brain tumor undergoes a risky surgery; an ER nurse fields romantic overtures from the people she treats; and two residents bond over their differences from their colleagues.
A man with a liver disease needs a transplant and hopes to live long enough for his daughter's wedding; a trauma surgeon finds his groove in New York after leaving New Orleans in the aftermath of Hurricane Katrina; ER nurses deal with demanding patients, including an intoxicated man who has to be subdued by security guards.
A woman with cystic fibrosis needs new lungs; an ER nurse makes a startling personal decision after hearing an elderly couple's story about their 65-year marriage; surgical residents share tales of hazing by senior surgeons.
A man with an eating disorder that compels him to eat metallic objects is treated by a trauma surgeon who was once an undocumented immigrant; a pediatric surgeon discusses a risky procedure to remove a tumor from a 4-year-old girl's heart; ER nurses try to restore a man's heartbeat; an old-school surgeon doesn't pull any punches with his residents, but he backs up his criticisms with his skills in the operating room.
A rash of violence on a Friday night keeps a surgical resident busy; a Gulf War veteran anxiously waits for a donor heart; an ER nurse treats a woman who was in a taxi accident and a bouncer arrested for fighting; Dr. Mehmet Oz prepares for a colonoscopy, and later quizzes colleagues about their diets.
A single mother with breast cancer learns whether or not the disease has spread; a surgical resident receives lighthearted marital advice from a colleague; a first-year emergency-medicine resident's even temper helps him deal with inebriated patients and treat a woman injured in a car accident, but his self-control abandons him during a prank by his coworkers.
A trauma surgeon counsels the family of a man who was run over by a vehicle in the street; Dr. Mehmet Oz performs a heart-valve replacement on an elderly woman; a pediatric surgeon operates on a newborn with multiple heart abnormalities; an ER doctor is serenaded by a patient who needs stitches in his hand.
In the series finale, a banker and mother undergoes a risky cancer operation known as ex vivo; a cardiac surgeon acknowledges the unpredictability of a career in medicine; a 13-year-old with Crohn's disease could be a candidate for a new colon surgery; and a young married couple often work together as surgical residents.