| Name (Sort) | Character (Sort) | |
| •Richard Mulligan | played | Dr. Harry Weston |
| •Kristy McNichol | played | Barbara Weston (S01-S05) |
| •Dinah Manoff | played | Carol Weston |
| •David Leisure | played | Charley Dietz |
| •Park Overall | played | Laverne Todd |
| •Lisa Rieffel | played | Emily Weston (S05, episodes 107-120) |
| •Marsha Warfield | played | Dr. Maxine Douglas (S06, S07) |
| •Estelle Getty | played | Sophia Petrillo (S06,S07) |
| •Bear the Dog | played | Dreyfuss |