This show is about two distant cousins, Ryan Dallion and Micki Foster, who inherit an antique shop named Curious Goods from their Uncle Lewis Vendredi. They are unaware that Vendredi made a pact with the Devil to sell cursed antiques, and when he tried to back out the Devil came to claim his soul. The cousins sell the antiques to unsuspecting buyers, then realize too late what they've done. Now Ryan and Micki team up with their uncle's innocent partner Jack Marshak, an occultist who purchased the antiques for Vendredi. Using Lewis' manifest, they track the sales and try to recover the antiques, each of which gives its owner special powers in return for some kind of sacrifice: typically human lives.

Late in the second season, the trio got involved with Johnny Ventura, whose father was killed by an antique wielder. He helped them in their investigations and when Ryan had to leave at the beginning of the third season, Johnny helped out Micki and Jack full-time. They occasionally ran into magical artifacts that weren't antiques, but for the most part they'd recover the indestructible antiques and store them in the vault below the antique store that they used as their base of operations.