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Season 1

1 :01x01 - You're Not Alone

Sep/09/2004
A New Yorker mysteriously turns ill in the middle of the street. Dr. Stephen Connor has to quit his son's baseball game and go to work with his NIH team to find out the cause of this situation and to find a cure before it's too late. Meanwhile, Dr. Miles McCabe is assigned to a hospital in Richmond, Virginia to investigate strange bruises on a baby.
Guest Stars: Clare Carey as Lisa Connor | E.J. Callahan as Landlord | P.D. Mani as Operator | Mike Randleman as Glen Harvey | John Bishop (1) as Brian Haskel | Elizabeth Sampson as Waitress | Dilva Henry as News Anchor | Donna M. Duffy as Nurse | Chris J. Kelly as Jack Connor | David Koff as Coach | Aloma Wright as Desk Nurse | Stephen Markle as Dr. Strickland | Karis Campbell as Kelly Leslie | Michael Nouri as Wes Douglas | Rich Hutchman as Eric Novack | Glenn Plummer as Daryl Cooly | Conor O'Farrell as Dr. Gorden | Kerry Carney as Dawn Haskel | Amanda Carlin as D.A. Jane Musgrave | Satya Lee as Asian Woman
Director: Marc Buckland

2 :01x02 - In Bloom

Sep/10/2004
Four teenage girls are struck with encephalitis. The NIH is summoned to fine the cause and the cure before time runs out. However what's thought to be STD (Sexual Transmitted Disease) wasn't what it appears to be and a pair of pants holds the key to the truth.
Guest Stars: Natalija Nogulich as Dahlia | Byrant Fox (2) as EMT #1 | Moira Price as Connie Sipe | Erica Mer as Charlotte Raymond | Cheryl White as Sylvia Townsend | Patty Cornell as Nurse | Mark Derwin as Paul Kendall | Shea Whigham as Barrett Fidler | Edward Lee Johnson (1) as EMT #2 | Katija Pevec as Ruby Willens | Scott Allan Campbell as Tamra's Father | Edward Edwards as Lorenzo Whiteside | James Moses Black as Terry
Director: Marc Buckland
Songs: Kid Gloves -- Why

3 :01x03 - Coming Home

Sep/17/2004
Dr. Connor and company are summoned by the US Army to investigate four Gulf War soldiers who recently came back with a lethal pulmonary disease. Powell believes it's Gulf War syndrome, until Connor finds out that several old citizens who haven't gone to war, also have it too.
Guest Stars: Marc D. Wilson as Officer Cortez | David Rountree as Officer Gorden | Jack Baker (1) as Priest | Daniel Graves as Pharmacist | Julia Silverman as Shirley Morris | Marshall Cook as Richard Henderson | Chris J. Kelly as Jack Connor | Veronique Vicari as Brenda | Alissa Dean as Shelly | Carmen Argenziano as Lt. Col. Bartek | Shea Whigham as Barrett Fidler | Lesley Fera as Gladys Halperin | Theo Rossi as PFC Joe Vasquez | Clare Carey as Lisa Connor | Jenica Bergere as Renee | Jacory Gums as Soldier
Director: Rick Wallace
Writer: Mark Israel
Songs: Boss House -- Hiding in the Light, Gary Jules -- Mad World

4 :01x04 - Escape

Sep/24/2004
Dr. Connor, Miles, and Frank are summoned to a Bahama resort to investigate why adult vacationers are starting to fall ill. But when the children also start to fall ill, the team realize they don't have much time left. Meanwhile, Durant and Rossi are in Miami to investigate an illness of an old man.
Guest Stars: Alyssa Shafer as Gracie Harring | Sarah Avery as Julie | Kristen Ariza as Staff Babysitter | Lonnie Hughes as Dr. Clement Morris | Wil Albert as Gerald Borman | Elena Finney as Kim | Andrew Abelson as Vaughn Kazerian | Johnny Sneed as Dan Harring | Lydia Blanco as Anel Diaz | Christina Chang as Jenny Small | Tracy Middendorf as Anne Harring | Patrick Fabian as Gary Riesen | Tony Perez as Raymond Diaz
Director: Marc Buckland
Writer: Daniel Arkin
Songs: Weezer -- Island In The Sun

5 :01x05 - Progeny

Oct/01/2004
The team is split up to investigate two different cases. Connor, McCabe, and Powell are summoned to a Caribbean resort to investigate adults with a strange respiratory problem. Meanwhile, Durant and Rossi stays in Miami to investigate an illness of an old man.
Guest Stars: Adam Taylor Gordon as Joey White | Deborah Geffner as Lucy Martin | Frank Novak (1) as Sherman | Kavita Patil as Dr. Ansuya Patel | Steve Seagren as Ted Martin | Corinne Reilly as Leslie White | Mik Scriba as Peter Smith | Kayla Mae Maloney as Sabrina Martin | Peter Outerbridge as Clark White | Gregory Itzin as Howard Lewson | Andrea Thompson as Dr. Lois McCarthy
Director: Rick Wallace

6 :01x06 - Team

Oct/15/2004
When several girls at a Midwestern College fall ill to a deadly disease, Dr. Conors and his team are summoned to find the cause. The team will soon find out these girls are not suffering from the same disease and a lipstick holds the answer to all the riddles.
Guest Stars: Jessica Osekowsky as Wendy | Cameron Bender as Steven Dewalt | Terry Savage as Football Player | Peter Pergelides as Chef | Miracle Laurie as Veronica | Jessica Webster as Amy Jenkins | Shanna Collins as Rebecca Steven | Robin Bartlett as Dr. Salgado | Dean Norris as David Weiner | Rand Holdren as Peter Warren | Page Kennedy as Gorden Kraft | Jamie Martz as Ryan Uteg | Brooke D'Orsay as Melissa Getemer
Director: Guy Ferland
Songs: Boss House -- It's All About Respect, Zero 7 -- Somersault

7 :01x07 - Alienation

Oct/29/2004
A woman faints during her bridal shower. Dr. Stephen Connor and his crew travel to Philadelphia to investigate as more patients rush in the medical center. As the team try to put puzzle together, they realize they got a case of anthrax at hand.
Guest Stars: M. Martin Mapoma as Ian Adoti | Ingrid Sanai Buron as Clerk | Michelle Merring as Ashley | Dave Fennoy as Flute Musican | Fredson Mayiek as Wali Tande | Mandy McMillian as Melanie | Elyse Donalson as Dr. Eckhart | Yvans Jourdain as Dr. Onyuke | Art Chudabala as Alex Ling | Glenn Morshower as Matt Borman | Jeffrey Scott Kelly as Randall Hodge | John Wesley as Mr. Ndudu | Melinda Page Hamilton as Sarah Doyle
Director: Michael Fresco
Writer: Ayanna Floyd
Songs: Angilalanga -- Africa Today, Andrea Matthews -- Back and Forth, Global Beats 5 Alarm -- Kenyan Quest

8 :01x08 - Mutation

Nov/05/2004
The NIH is summoned to a small town in Virginia, where some people in a small town is infected with a strange virus. Struggling to find out what that virus is, more and more people are checking in the hospital with the same virus. Can Dr. Stephen Connor and his team find the true identity of the virus and the antibiotics in time before the entire town is infected?
Guest Stars: Phil Reeves as Sheriff | Chace Elliott as Elliot | Matt Casper as Donnie Brown | Richard Roat as Judge Henry | Jolie Jenkins as Lillith | Gerry Black as Stanley Price | Stacy Barnhisel as Emily Harris | Phyllis Applegate as Iris Price
Director: Marc Buckland

9 :01x09 - Little Girl

Nov/12/2004
A little girl has fallen ill and needs a healthy bone marrow. However, her adopted parents recently died due to an identical aplastic anemia. As the NIH tries to find out the source of this illness, Eva Rossi must find the right bone marrow transplant from her biological parents before it's too late.
Guest Stars: Marcy Goldman as Ms. Tuttles | Blaire Restaneo as Carla Beyer | Catherine Wadkins as Cyndi Harmon | Barbara Tarbuck as Eunice | Ray Hale as Husband | Sarah Jones (1) as Belinda | Jeff D'Agostino as Randy | Duane Whitaker as Bar Owner | Kirsten Severson as Assistant | Randy Frazier as Clayton Beyer | Dawnn Lewis as Dr. Burton
Director: Paul Holahan
Songs: Let The Moonlight Shine -- Kid Gloves, Kid Gloves -- The Imperfect Grace, Boss House -- Wounded

10 :01x10 - Price of Pleasure

Nov/19/2004
Several females check into a LA hospital after fallen ill due to a deadly disease. The NIH is summoned into the scene and are ask to find the cause and a cure. Their commonality? They all are adult film actresses, so the team immediately thinks some kind of STD or HIV are involve. But when the test comes back negative for those disease, the team has to search elsewhere for the answer.
Guest Stars: Karen Strassman as Jenna Kirkland | Colton Shires as Boy (Kirkland's Son) | Jessica Landon as Lisa Marquis (Van Adams) | Carissa Koutantzis as Production Assistant | Eddie Richardson as Nurse | Mykel Shannon Jenkins as David Thorn | Kevin E. West as Trevor Johnson | Rosalind Chao as Dr. Kramer | Michael Ironside as Ben Graybridge | Maurice Godin as Dr. John Bender | Paul Schulze as Andrew Kirkland | Enrique Castillo as Manager
Director: Norberto Barba
Songs: Wild Whirled -- Lazy ol' Blues, Snow Patrol -- Somewhere a Clock is Ticking

11 :01x11 - The Unclean

Dec/03/2004
Several patients have mysterious infected bateria on them after having surgery. It's up to the NIH to stop this "Angel of Death", who also has a past that no one should be proud of.
Guest Stars: Don Perry as Mr. Geraci | Jeremiah Birkett as Raymond Jeter | Joyce Guy as Dr. Thomas | Lisa Waltz as Ms. Johnson | Katie MacNicol as Nurse Molly Kimbrell | Henri Lubatti as Nurse Tim Miller | Mark Harelik as Dr. Lester | Shannon Marie Woodward as Danielle Johnson | Kathryn Harrold as Carla Ballard
Director: Elodie Keene
Writer: Mark Dodson
Songs: Massive Attack -- Future Proof

12 :01x12 - Spiked

Jan/07/2005
Several people are struck with a disease that Dr. Connor and his team have no clue on what it is. They suspect the disease are being transfer from seals to humans. The team swipe the beach clean, but find nothing. Frank Powell retrieve some garbage that floated ashore, thinking that it's the waste that is infecting the seals and humans. But the results also come back negative.
Guest Stars: Rachel Wacholder as Dana | Jen Pavley as Sharon | Katrina Nelson as Beth Miller | Noel Conlon as Joe Burris | Colby French as Keith Jacobs | Jim Holmes as Unknown | Erich Anderson as Landsbury | Lauren C. Mayhew as Sudie Miller | Marguerite MacIntyre as Dr. Karen Lowe
Director: Tucker Gates
Writer: Peter Egan
Songs: Yellowcard -- Back Home, Matthew Ryan (1) -- Irrelevant

13 :01x13 - Tribe

Jan/14/2005
Several people in a Montana camp resort got infected with a disease, presumably smallpox. Dr. Stephen Connor and the NIH are summoned to the scene to try to stop the spread of the disease. But when the FBI show up, there is indication that this may be a terrorist's plot to spread the disease.
Guest Stars: Zachary Winard as Jeff McDaniel | Colleen McGrann as Ellie Beck | Leanna Campbell as Erica | Lance Carter as Jack | Robert Peters (2) as Kevin McDaniel | Neal Matarazzo as Bill Beck | Gil Birmingham as Birmingham | Laura Marano as Brooke Beck | Kevin Kilner as Paul Maloney
Director: Marc Buckland

14 :01x14 - Ice Station

Jan/28/2005
Several people in a station in Antarctica are getting infected with an aggressive ammonia. What's even worst is one of the NIH's own is also infected and the team may have difficulty getting aid because of a strong storm outside.
Guest Stars: Jason Peck as Helecopter Pilot | LaNiesha Irvin as Tesha Powell | Mark Ankeny as Colonel Brown | Klea Scott as Kim Powell | Russell Soder as Jeff | Taylor Nichols as Raymond | Betsy Brandt as Karen Banks
Director: Jeffrey Reiner
Writer: Mark Dodson

15 :01x15 - Mousetrap

Feb/04/2005
A plague outbreak is discovered near Baltimore. While the NIH tries to find the source and stop it from spreading. Along the way, they find some dirty cops trying to cover up a murder. Viewers also get a glimpse on Dr. Stephen Connor's past.
Guest Stars: Eddie Magaña as Det. Garcia | Jules Theodore as T-Bone | Daniel Gibbons as Connor's Dad | Michael Peterson (1) as Young Connor | Bobby T. McLaughlin (2) as Lawrence Dinkins | Deji LaRay as Murphy (as Deji Olasimbo) | Doug Wax as Doctor | Paul Butcher as Tim Wayne | Hayden Tank as Michael Wayne | Michael Cudlitz as Lt. Troy Adams | Deborah Carson as Connor's Mom | Tim Griffin as Det. Chris Leinberger | Karina Logue as Claire Leinberger | Timothy Davis-Reed as Keith Wayne | Maria McCann as Mindy Wayne
Director: Norberto Barba

16 :01x16 - Survivor

Feb/11/2005
Dr. Stephen Connor splits the team into two. Miles McCabe and Eva Rossi investigate a case where several soldiers' wives are all having strange miscarriages. Connor, Natalie Durrant, and Frank Powell investigate why some patients are having a strange defect that in their legs.
Guest Stars: Jimmy Walker, Jr. as Night Janitor | Lexi Ainsworth as Kaitlin Ronson | Sarah Mack as Amy Owens | Christina Gianaris as Rebecca England | Brooke Blau as Lexi Owens | Vivien Blau as Lexi Owens | John Hartmann as Dr. Hall | Adam Lieberman as Daniel Metcalf | Lola Glaudini as Meredith Beck | Megan Henning as Nancy Hain | Jose Pablo Cantillo as Rick Hain | Heath Freeman as Josh | Jan Devereaux as Mrs. Ronson | Allen Williams as Gary England
Director: Craig Zisk
Writer: Ayanna Floyd

17 :01x17 - Half Life (2)

Feb/18/2005
In a rare crossover with several casts of Third Watch, Dr. Stephen Connor and his team heads to NYC to uncover a multiplying virus before it spreads anymore. Stephen teams up with the NYPD to find patient zero, the one who is carrying the disease and spreading it around the city.
Guest Stars: Michael Keenan as ESU Officer | James Smith (2) as Artis McDonald | Mark Chaet as Harris | Randy Ryan as Richard Rush | Victor McCay as Mr. Finch | Jake Muxworthy as Harry Rush | Yvonne Jung as Holly Levine | Molly Price as Detective Faith Yokas | Anthony Ruivivar as Carlos Nieto
Director: Roxann Dawson
Writer: David Ehrman

18 :01x18 - The Black Book

Feb/25/2005
Two politicians and a cop are infected with what is first suspected as a STD (Sexual Transmitted Disease). But this strange disease is killing patients at very fast rate and Dr. Stephen Connor and Co. must find the source of this virus as fast as they can.
Guest Stars: Walter Cox (1) as Reporter | Douglas Purdy as Mark | Lana Antonova as Nicoletta | Ursula Whittaker as Mindy Manning | Janelle Giumarra as Didi Lomax | David Noroña as Kenneth McBride | Gil Glasgow (1) as Jack Jacobs | Larissa Laskin as Donna Laurence | Robert Curtis Brown as Doug Laurence | Susanna Thompson as Dr. Kate Ewing
Director: Elodie Keene

19 :01x19 - Mission La Roca (1)

Mar/18/2005
An outbreak occurs in Mexico and the NIH sent several teams there to help with the relieve effort and to find the source of this disease. When they lost contact with Dr. Natalie Durant, Dr. Miles McCabe, Eva Rossi, Dr. Stephen Connor and Frank Powell decide to travel to the there themselves to help find them.
Guest Stars: Frank Gallegos as Driver | Bernardo Verdugo as Young Father | Ulysses Estrada as Juan | Billy Concha as Insurgent | Diana Rios as Marilu | Juan Carlos Cantu as Priest | Oliver Patrick Sandino as Emberto Zuniga | Katie Mitchell as Reporter | Jesse Borrego as Antonio Baracas | Jeremy Ray Valdez as Nestor | Susanna Thompson as Dr. Kate Ewing | Claudia Besso as Kris Von Getz
Director: Karen Gaviola

20 :01x20 - Mission La Roca (2)

Mar/25/2005
As Dr. Natalie Durant continues to try to find what kind of disease they are dealing with, Dr. Stephen Connor is at church Mission La Roca trying to rescue Dr. Miles McCabe and his patients to the hospital before the church collapses.
Guest Stars: Oliver Patrick Sandino as Emberto Zuniga | Tiffany O'Hara as Nurse | Marco Pelaez as Augustin Zuniga | Sam Ayers as Aid Worker | Ulysses Estrada as Juan | Jeremy Ray Valdez as Nestor | Alex Wexo as Doctor | Richard Yniguez as Minister Cabrera | Katie Mitchell as Reporter | Claudia Besso as Kris Von Getz | Susanna Thompson as Dr. Kate Ewing | Jesse Borrego as Antonio Baracas | Jenny Gago as Alma Diaz | Diana Rios as Marilu
Director: Paul Holahan
Warning: Medical Investigation guide may contain spoilers
Classification: Scripted
Genre: Drama
Status: Canceled/Ended
Network: NBC ( USA)
Airs: Fridays at 10:00 pm
Runtime: 60 Minutes
Premiere: September 09, 2004
Ended: March 25, 2005
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