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•Swoosie Kurtz

played

Alexandra 'Alex' Reed Halsey Barker

•Sela Ward

played

Theodora 'Teddy' Reed Margolis Falconer Sorenson

•Patricia Kalember

played

Georgiana "Georgie" Reed Whitsig

•Julianne Phillips

played

Francesca 'Frankie' Reed Margolis (S01-S05)

•Elizabeth Hoffman

played

Beatrice 'Bea' Reed Ventnor

•Ed Marinaro

played

Mitchel 'Mitch' Margolis (S01-S04)

•Garrett M. Brown (1)

played

John Whitsing (S01-S05)

•Heather McAdam

played

Catherine "Cat" Anne Margolis

•Jo Anderson (1)

played

Dr. Charlotte "Charley" Bennett Hayes #1 (S04-S05)

•Sheila Kelley (1)

played

Dr. Charlotte "Charley" Bennett Hayes #2 (S06)

•Ashley Judd

played

Reed Lyn Halsey Philby #2 (1991-1994)

•David Dukes (1)

played

Dr. Wade Halsey (1991-1993)

•Dustin Berkovitz

played

Evan Whitsig

•Eric Close

played

William 'Billy' Griffin (1995-1996)

•George Clooney

played

Detective James Falconer (1993-1994)

•John Wesley Shipp

played

Lucky (1994-1995)

•Kathryn Zaremba

played

Roxie Whatley (1994)

•Kathy Wagner

played

Reed Lyn Halsey Philby #1 (1991)

•Mark Frankel

played

Simon Bolt/Lymen Smelt ((1992-1993))

•Michael Whaley

played

Dr. Wesley Hayes (1995-1996)

•Nora Dunn

played

Norma Lear (1993-1996)

•Noëlle Parker

played

Reed Lyn Halsey Philby #3 (1995-1996)

•Philip Sterling

played

Truman Ventnor (1991-1995)

•Robert Klein (1)

played

Big Al Barker (1993-1996)

•Ryan Francis

played

Trevor Michael Whitsig (1991-1995)

•Sean Nelson

played

Jesse (1995-1996)

•Stephen Collins (1)

played

Dr. Gabriel Sorenson (1995-1996)

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