The Thornberrys spend the night in the middle of the African savannah. Eliza decides it is the perfect opportunity to talk to lions, her favorite animal, only to find that her sister could be the lion's dinner.
Eliza and Darwin get into a fight, so Darwin heads off into the Manaus jungle to prove he isn't afraid to live in the wild. Horrified, Darwin tries to seek shelter in a hut, only to find it's occupied by some hungry natives.
A group of marmosets invade the Thornberry's campsite, and with her parents gone, and Debbie off trying to make herself shampoo, Eliza decides to play with the little primates. The marmosets start to cause havoc, Eliza starts to realize that Donnie could get hurt.
The Thornberrys are at the Galapagos Islands, and Eliza and Debbie find a map. Eliza is convinced that it's a real treasure map, and Debbie reluctantly follows. Once they locate the gold, Eliza and Debbie fight over who deserves the gold.
When Nigel, Marianne, and Debbie leave without Eliza, Darwin, and Donnie, they have to race through the jungle of Zaire in order to keep up.
A group of jaguars believe Eliza is their long lost queen when Eliza and Darwin venture into a mysterious temple. Eliza goes along with the idea, and fill the jaguars with all sorts of stories. Eliza finds herself in a tangle of lies when the jaguars find out that she's a fraud.
After befriending a kangaroo, Eliza agrees to babysit her wild son Joey.
With no means of transportation, the Thornberrys are stranded in the middle of a desert during a drought. Nigel seeks help, while Eliza befriends a group of dehydrated animals.
Nigel is invited back home to England, where he is to be knighted by the Queen, and is also offered a job at Oxford University. Eliza becomes horrified at the thought of no longer traveling the world.
After being knighted, Nigel must make a tough choice between settling town, or traveling the world.
The Thornberry's are in Antarctica to film the penguins, and when Eliza encounters an injured penguin. Eliza, whom wants to be a veteranarian, decides to help her, but Eliza ends up worsening things.
After staying with the Thornberrys for a while, Shane wants to leave, but Eliza wants to tell him she likes him, but they get in a fight.