After experiencing a rough slide, Rembrandt and Maggie see Colin is nowhere to be found. More disturbing, they meet a stranger claiming he is Quinn Mallory. Rembrandt and Maggie learn too late that this is all a part of an evil genius' desperate plan to save his life.
Diana tries using a university lab to find a way to separate Quinn and Mallory, which leads to her first encounter with her double, a struggling single mother. Meanwhile, Mallory experiences violent flashbacks from Quinn's life.
The Sliders arrive in a barren wasteland, where the timer is inoperable. Worse yet, they find themselves forced to take part in a never ending battle between Kromaggs and soldiers from Quinn's home world, who are guarding a mysterious bunker.
The Sliders arrive on a small island, with a very sick Maggie in tow. While looking for help, Rembrandt, Mallory and Diana meet the monks of a secluded monastery. Reluctantly, the monks allow them to stay and give Maggie medical attention. But the Sliders soon learn the monks have a secret and won't allow them to leave.
Just before sliding out and escaping a small army, Mallory is shot with a laser beam and paralyzed. His only chance of walking again lies in a group of spiritual healers, but their cure could be much worse than being paralyzed.
After trying to buy a candy bar, Maggie is kidnapped by a corporate conglomerate that uses data codes to control commerce.
The Sliders arrive on a world where Prohibition still exists, only it was caffeine that was outlawed. They meet a nightclub owner whose lover was murdered by a gang dealing in bootleg coffee.
Rembrandt experiences a strange dream in which Wade is trying to contact him and bring him to her. The others have their doubts until a spatial fold opens before them. On the other side, they find Wade is somehow being used in a plan to attack Kromagg Prime.
A malfunctioning timer deposits the Sliders underwater in the Pacific Ocean. A merchant ship picks them up, but is taking them out of their sliding radius and decreasing the likelihood of a safe slide. Their only chance is to join up with a pirate crew to get back to California.
The Sliders confront Dr. Geiger again, in a collapsing dimension full of innocent victims.
The Sliders arrive in the middle of a rally, surprisingly being held in their honor. They learn they are the subjects of a religion called Slidology, founded by a man with psychic abilities. He has been following their adventures and warns that on their next slide, they will all die.