The Sliders arrive in an airplane, which begins to crash land. However, they learn that it is just a simulation and the beginning of deadly game show in which the losers die.
The Sliders meet a scientist attempting to develop sliding technology and offers to help them get home if they help her. However, they soon learn that she has an ulterior motive.
Songs: Cleavant Derricks -- I'd Pawn My Gold Crown For You
On a world suffering from electric tornadoes, the Sliders find safety in a protected village. However, because electrical devices attract the tornadoes, the leader takes away their timer.
The Sliders find a world in which time moves slightly slower, resulting in a twelve-year difference. Quinn then meets his younger self and tries to alter a traumatic event he had with bullies.
Wade is targeted by a group of people with the ability to enter the dreams of others.
On a desert world with little water, the Sliders rescue a girl who had been kidnapped because of her ability to locate water.
The Sliders arrive on a world where physics seemingly doesn't apply, allowing magic to exist. Quinn is thought to be part of a line of wizards, prompting an evil warlock to kidnap him.
The Sliders arrive on a world in which Los Angeles is rich with oil. However, when they previously slid, they unknowingly brought along a sentient flame.
The Sliders arrive on a world in which the United States is a monarchy, and Rembrandt is Duke of Hemmingshire. When Rembrandt sees Danielle, a woman he recognizes and who in actuality is the Duchess of this world, apparently about to give birth, he goes to help. However, what he doesn't know is that the husbands give birth on this world.
Quinn is arrested for crimes committed by his double, and he is then tried on a game show where his fate will be decided by the audience.
After arriving on a world inhabited only by androids, Quinn and Rembrandt are taken captive by the creator of the androids, who plans on transferring their minds into android duplicates.
After finding an abandoned child, the Sliders get jobs in a giant mall in the sky in order to find its mother.
The Sliders arrive on a world where the government forces everyone to work at maximum efficiency, and sends "fractures" who break from the stress to theme parks where they are brainwashed into role-playing fictional characters. When a grumpy Arturo is diagnosed as a fracture, he is sent to one such park and brainwashed to play a 19th century detective on the trail of Jack the Ripper.
In a world descended from Egyptian culture, the Sliders end up breaking a cultural more and Wade and Quinn are respectively sentenced to death at the pincers of a scarab and medical experimentation.
The Sliders arrive in a small community that is distrustful of outsiders. When they hook up with a geologist looking for her missing assistant, they stumble upon the town's sinister secret.
The Sliders arrive on an Earth threatened by lethal radiation Pulsars that are slowly eating away at Earth, the only chance the population has for survival is to make use of the Sliding technology developed by their military. With Quinn and Arturo's help, preparations begin for an evacuation, but a more chilling mystery begins to unfold when a large body count of coma victims begins piling up...
At long last, Quinn has the coordinates to Earth Prime, but its atmosphere is deadly to Maggie and her people. While Quinn and Maggie continue to search for a hospitable world, Wade works to perfect the Slide list to Rickman's specifications and Arturo tries to modify the timer to save more people.
The Sliders arrive on a world where civilization has fallen to a bacteria that creates flesh-eating zombies. Shortly after arriving, Quinn is bitten, and starts turning into a zombie as well!
The Sliders narrowly escape from a world filled with parasitic creatures, but not before Maggie becomes infected. On the next world, the parasite searches for a host in order to reproduce.
Wade and Rembrandt recall a particularly harrowing adventure on a world at the mercy of catastrophic earthquakes. When Wade falls beneath the earth, Quinn embarks on a risky rescue mission while Rembrandt and Arturo fall into the company of the less-than-friendly natives.
The Sliders finally track Rickman down in a town bordered by a sulfurious fog. When Quinn and Maggie are captured, Quinn is forced to confront a familiar face.
Quinn and Rembrandt head down to Mexico to blow off a little steam. Getting back into the United States turns out to be a bit of a problem when they get mixed up in an illegal snake trade and find themselves stuck in the middle of a jungle, surrounded by deadly snakes and the tobacco cartel. Meanwhile, Wade and Maggie run into problems of their own while they search for the other Sliders.
The Sliders arrive back at the New World they helped Rickman colonise, shortly after the Colonel arrives himself. While the Sliders try to figure out how to stop Rickman, they discover this parallel world's unusual inhabitants: dinosaurs, including a particularly aggressive Tyrannosaurus Rex.
Wade becomes infatuated with Stoker, a rock band whose members are secretly vampires. Meanwhile, the other Sliders try to find clues to Rickman's whereabouts before he escapes them again.
The Sliders splash down near an island inhabited by humans cross-bred with animals, the results of painful experimentation's by the local scientist. When the timer is taken by a now feral and partially transformed Colonel Rickman,Quinn must bargain with the scientist to escape, but Rembrandt's infatuation with a cross-breed slave puts the alliance at risk...