"Snooki & JWOWW" follows the two well-known characters of "Jersey Shore" Nicole "Snooki" Polizzi and Jenni "JWOWW" Farley. Each week they travel around Jersey City and move in together. With their romantic relationships on hold, the two "besties" get to have fun and party. However, when Nicole tells Jenni the surpise that she is pregnant, they have to change their plans of drinking and partying to doing things for the soon-to-be birth of Nicole's first born.
The two show that they can be mature as they have one last "hurrah" before settling down with their future spouses. In the meanwhile, they have to navigate through the fact that Nicole is pregnant and the "partying" is going to have to be scaled down a bit. As they have fun with one another living together, they soon find out that living with someone isn't as easy as it sounds.