Three stories of living life to the fullest, despite illness, age or any obstacle.
Three inspiring people switch gears in life in order to pursue their dreams.
Jackie and David Siegel talk about building the largest home in America when the economy crashed in 2008.
Sisters Josie Cavaluzzi, Teresa Dalquist and Mary Bartnicki, all in their 80s, give their take on sex.
Documentarian Morgan Spurlock joins Jeff to talk about what makes a man.
A woman not feeling well checks herself into a hospital and comes out with her limbs amputated; an American is held hostage in Iraq for more than 300 days.
Reality stars Jeff Lewis and Zoila Chavez; a father changes his life to bring joy to his teen daughter; a man teaches his goofy dance all over the world.
A man who posted his phone number around New York City in order to find someone to talk to ends up changing people's lives; a couple rekindles their childhood love 40 years later.
Mike Rowe shares some of the unique jobs he has done on his hit TV show; an adult-toy reviewer; a fortune-cookie writer; the producer who comes up with the challenges on ``Survivor.''
A woman sets out to make a new friend every day for a year; a man conducts bizarre and fascinating life experiments; a blogger packs up and moves to another country every four months.
Comic Margaret Cho and singer Chely Wright discuss race, stereotypes, labels and political correctness.
Guests who have experienced terrible breakups include reality TV star Brandi Glanville, a woman whose videos about her divorce went viral online, and a woman who announced her husband's betrayal on a home-for-sale sign.
People living in unique situations include a woman who spent only $159 on her wedding.
Actor Jon Cryer.
A newly unemployed man tried to cheat his way to the top by robbing banks for a living; a woman climbed the corporate ladder by lying on her resume and forging her diploma; a man sued his wife's lover.
Judy Sheindlin, known as Judge Judy, discusses her career.
Supermodel Paulina Porizkova talks about getting older; a health update from Kelly.
Howie Mandel talks about his career and the dare that changed his life.
Comedian Wayne Brady talks about women; the ``Krazy Coupon Ladies'' share tips on shopping.
The star of ``NCIS'' Pauley Perrette chats with Jeff.
A woman talks about being locked inside a storage unit for more than a decade before escaping; Lord Robert Walters (``Secret Princes'') discusses his undercover journey to find love in America.
``Push Girls'' stars Auti, Angela and Tiphany, who survived accidents and are now in wheelchairs, discuss dating and making love; a woman who was dumped by her husband of 10 years via a text message; chef Fabio Viviani answers audience questions.
Deepak Chopra and his son, Gotham, provide a glimpse into the father's private life and his relationship with his family; a 10-year-old boy who built a functioning arcade using only cardboard and household supplies.
A same-sex couple discuss the challenges they faced when trying to adopt a baby, including the month when they didn't know if the birth mother would take the baby back; a mother steps into the middle of gang conflicts in Chicago.
Actress Melanie Lynskey talks about having to overcome the odds to achieve success in Hollywood; actor Oliver Platt (``The Oranges'') discusses marriage and parenting.
Business magnate Mark Cuban tells how to make professional dreams come true.
Actress Gina Gershon; cat behaviorist Jackson Galaxy.
Drag queen RuPaul; party planner Jennifer Gilbert.
Damien Echols, who spent 18 years on death row for a crime he did not commit, and his wife, Lorri.
A woman survives a deadly plane crash; a man finds a wedding ring at the bottom of a garbage truck; a man can win every game at a carnival.
A matchmaker takes her clients out to help them get dates; comic Rove McManus
Journalist Lisa Ling; a millionaire spirals into an out-of-control shopping addiction and loses everything.
A woman's face blindness makes her unable to recognize anyone; an Ambush Adventure gives a woman a shot at television stardom.
Actress Vivica Fox.
A young woman with no arms proves that nothing is out of her reach; a young man tells of forgiving the father who injected him with HIV-infected blood when he was just an infant.
Actress Lisa Whelchel (``The Facts of Life'').
Actor Joey Lawrence; actress Daniela Ruah.
Jeff poses as a psychic and gives readings using tricks taught to him by a former professional medium who wants to blow the whistle on the industry; hypnotist Tom Silver.
A mother makes international headlines by going on strike in her own home; how to get a family to pitch in without having to throw in the towel.
Actress Jennie Garth (``Beverly Hills, 90210'').
``Days of our Lives'' stars Kristian Alfonso, Drake Hogestyn, James Scott, Galen Gering, Bryan Dattilo and Deidre Hall.
Celebrity makeup artist Scott Barnes; a woman's love of cosmetic surgery breaks the bank and her marriage.
Actress Marlee Matlin discusses being deaf in Hollywood; comic James Adomian.
Two adult film stars; a woman behind a website dedicated to presenting a more realistic depiction of sex.
Actress Kristen Bell; audience members get celebrity makeovers.
Actress Alison Sweeney.
A teen has Sleeping Beauty syndrome; a 12-year-old is unable to feel pain; a girl's disease is turning her into a human statue.
Transgendered guests change the lives of the people who love them.
Two women tell of being kidnapped and buried alive; a man survived an assassination attempt; a girl's parents sold her into slavery.
Three matchmakers go head-to-head to pick the ideal match for the same woman; Jeff hosts a mixer for an all-singles audience.
Deserving people receive surprises and giveaways; Jeff ambushes a man who helps underprivileged children; a couple gets a wedding ``do-over''; ``Real Housewives of New Jersey'' stars Brandi Glanville and Lisa Venderpump ambush fans.
Trainer Jillian Michaels shares how she overcame her weight issues; actress Marissa Jaret Winokur shows off her body after losing 60 pounds; seven people whose weight loss totals almost 900 pounds.
Singer Rick Springfield discusses his battle with depression and how infidelity almost ruined his marriage; Springfield performs some of his classic songs and surprises a fan.
Filmmaker Nev Schulman (``Catfish'') discusses documenting his online quest for love, which took a wrong turn, and his new reality show; ``Extreme Cougar Wives'' stars discuss dating younger men.
Actor Shemar Moore and the woman who has his heart; actress Deborah Ann Woll and boyfriend E.J. Scott.
Carter Oosterhouse (``Million Dollar Rooms'') discusses home decor; Dave Salmoni (``Frontier Earth'') and animals.
Author Jennifer Weiner discusses weight; comic Russell Peters; matchmaker Steve Ward; comic Michelle Buteau.
Polygamist Kody Brown and wives Meri, Janelle, Christine and Robyn and four of their 17 children.
Heckler Robin Ficker meets NBA star Isaiah Thomas; how online bullies nearly ruined a wedding; a woman's angry email response to a potential employer goes viral.
A DNA specialist meets with Jeff to reveal his genetic makeup, tracked back to prehistoric times, and offers insight into what DNA can tell; actor George Eads; four siblings separated 80 years ago discuss how they were reunited.
Actress Angela Kinsey; actress Elizabeth Perkins; one of Jeff's favorite authors.
Salina, Rynn, Blair and Lindsey of ``Married to the Army: Alaska''; chef Cat Cora creates holiday treats.
The stars of the show ``Doomsday Preppers'' tell about their preparations for the end of the world; the stars of ``Jungle Gold'' talk about risking their lives to mine for gold in Africa.
Actresses Jamie Gertz and Constance Zimmer.
An interview with the five remaining ``Survivor: Philippines'' castaways.
Actress Alana Stewart.
Actor Dwight Henry; a man spent 27 years in prison for a murder he did not commit; a couple spend their lives chasing tornadoes.
Actor Eric Roberts discusses his career and history of drug abuse; Indy 500 winner and ``Dancing With the Stars'' champion Helio Castroneves shows off his footwork and competes with Jeff in a racing simulation.
Race-car driver Danica Patrick discusses the dangers of her profession; blogger Jia Jiang discusses how his desire to seek out rejection has led to unexpected consequences.
Olympic gymnast Dominique Moceanu reveals the secret about the sister he parents never told her she had; a woman discusses discovering at age 15 that her father was a serial killer.
Cast members from ``The Shahs of Sunset'' discuss the show and respond to criticism.
Actor Hugh Jackman discusses his personal and professional lives before getting a surprise.
Louis Ortiz shows off his Barrack Obama impression. Plus Jeff meets people who's lives were turned into the movies 'The Blind Side' and 'The Sessions'.
A 9 year old play's 'Who's Right?'. Plus four moms who turned their ideas into million's of dollars.
Fitness trainer to the stars Jackie Warner shares fitness tips.
Chris Gaida talks about his life as a celebrity escort. Haley Strode is in the studio.
A new reality show is going to air showing the rare lives of preachers daughters.
Dominic Monaghan talks about his new series.
Miss Montana - Alexis Wineman is in the studio.
A blind man who competes in professional sports.
John Varvatos from 'Fashion Star' is on the show.
Two orphaned sisters reunited after 14 years help each other with motherhood. Plus Bill and Giuliana Rancic.
Tyrese Gibson looks inside mens minds.