Wendy Watson is an ordinary temp secretary who gets fired when a genetically modified monster goes berserk. This brings her into contact with... the Middleman, a special agent who contracts to take out mad scientists and evil spirits. She tags along on his newest case: looking into monkey business in the Mafia.
Wendy and the Middleman try to stop a Terracotta Warrior from releasing a hail of fire upon the Earth, by stopping him from sacrificing the Emperor's heir. Meanwhile, Lacey is fighting with Wendy over her protest activities.
Songs: The Submarines -- Maybe, The Chaos in Order -- Sideways
While the Middleman investigates a diamond theft, Wendy goes to the airport to pick up Sensei Ping, her soon-to-be martial arts trainer. But when Mexican wrestlers kidnap the martial arts master and abduct the Middleman, Wendy must make her way to Yucatan to save them.
Songs: The Go Find -- Beautiful Night, Senor Flavio -- Lucha Libre Lovers
A rich woman disappears while shopping and the Middleman and Wendy investigate. The trail leads to a group of gem-eating aliens hiding on Earth, aliens targeted by a mysterious hunter. Meanwhile, the Middleman conducts a series of pop quizzes to see if Wendy is ready to become a Middleman in the future, and Wendy deals with the emotional angst of Ben putting their breakup video on the Internet.
Songs: Arm's Way -- Pieces of You, The Russian Futurist -- Precious Metals, Scientific -- Strain My Heart
Wendy and the Middleman take on flesh-eating zombies with a taste for... fish?
Songs: Now, Now Every Children -- Everyone You Know, The Polyamorous Affair -- Merry Go Round, Layton -- That Time
The duo take on Cindy, the world's biggest and most dangerous fan of a boy-band.
Songs: Varsity Fanclub -- Future Love
Wendy and the Middleman have to find a cursed tuba that causes anyone who hears it to drown.
Songs: Pepi Ginsberg -- Nothing More, Au Revoir Simone -- Stars
A sorority is plagued by ghosts and Wendy has to go undercover to find out what's going on.
Songs: Camphor -- Daybreak, David Vandervelde -- Someone Like You, Time Traveller -- Sumthin About Her
When a super villain known as the Candle makes his return, the Middleman must turn to... the former Middleman. Guy Goddard.
Songs: French Kicks -- Carried Away, Emiliana Torrini -- Me and Armini, The Little Ones -- Morning Tide
An animated puppet holds the key to a mass resurrection of vampires across the Earth.
Songs: Walter Meego -- Baby Please, Chromeo -- Bonafied Lovin
When Ida is infested with alien nanobots and turns (more) evil, she tricks Wendy and the Middleman into shutting down the HQ.
Songs: The Russian Futurists -- Let's Get Ready to Crumble
The duo take on the evil Palindrome, a super-villain who inadvertently transports Wendy to a parallel universe.
Songs: Zeigeist -- Humanitarianism, Ladytron -- I'm Not Scared, Music Go Music -- Light of Love