Spider-Man and Nova must help the Guardians of the Galaxy face a threat that has followed them to Earth.
Spider-Man’s dream of joining the Avengers becomes a nightmare when Loki switches bodies with the web-slinger, turning his new teammates against him.
Spider-Man and his friends team up with the Avengers to stop Loki and Doctor Octopus from destroying New York City with an army of Venomized monsters.
Spider-Man must team up with the super hero wanna-be Flash Thompson, when the Beetle wants them both destroyed.
To make matters worse, Flash had once again been Venomized but insists he's fighting for good.
Spider-Man wants to recruit Cloak and Dagger as new warriors for his S.H.I.E.L.D. team.
However, things don't go as planned when they must help Doctor Strange battle Dormammu.
Peter Parker's intellectual rival, Amadeus Cho, obtains Tony Stark's Iron Spider armor.
At Nick Fury's request, Spidey must recruit the new Iron Spider however, Taskmaster attempts to seize the armor for himself.
Spider-Man encounters The Vulture. A mysterious thief whose memory loss sends him to Doc Oc for answers.
Spider-Man enlists the help of one of the X-Men, Wolverine, on his trip to the Savage Land to help track down Ka-Zar and put an end to his plot, but they have more on their hands when they uncover Taskmasker and Kraven have their own plans.
The cast of "Jessie" gets animated in this special crossover episode that finds the Manhattan nanny in possession of a medieval sword coveted by the infamous Morgan Le Fey. Jessie and Spider-Man team up to save Halloween and the world from Le Fay's evil plans.
The new team of teenage heroes put together by Spider-Man is given their first test when the Taskmaster puts the plan he has been working on into action, testing them to see if they can work as a team or falter in their first challenge.