Bailey takes on her first day as chief; April's marriage is in trouble and she struggles to face her problems; Meredith juggles her responsibilities; Amelia tries to define her relationship with Owen.
When Maggie gets an invitation to her ex-boyfriend's wedding, she starts to reevaluate her choices; Bailey's loyalty falls into question; Jo opens up to Stephanie about a secret; Alex must make a decision that will affect the lives of two babies.
Owen suggests the interns learn about breaking bad news to patients' families; Arizona's elderly patient tells her she will find love again; the sisters forget about the dinner party they're hosting.
Maggie ditches cooking duties at her sister's dinner party to rush to the hospital; April tries to avoid Jackson; Arizona waits to learn more about Callie's girlfriend.
A new resident transfers to Grey Sloan Memorial; Richard is uncertain how to advance his relationship with Maggie; a young boy from the Middle East needs treatment.
Tension rises as the doctors help a long-time patient; Bailey urges Ben to ask their roommate to leave; Arizona wants to start dating again.
As gossip continues to spread, a wildfire sends many firefighters to the hospital; Maggie tries to stay professional with Andrew at work; Alex's priorities are questioned.
A patient ends up brutally attacking Meredith. Penny finds out what happened and the doctors atetmpt to save Meredith.
Everybody attempts to deals with Meredith's trauma as Maggie and Callie perform a risky, experimental surgery on a teenager. Nathan and Owen continue to be at odds. Maggie and Andrew's relationship continues to progress.
Some flashbacks reveal the progression of April and Jackson's relationship.
A patient from Meredith's first surgery as an intern is back at to the hospital suffering with an aneurysm. Maggie believes that Richard knows about her relationship with Andrew.
Meredith, Bailey, Jackson, Callie and Jo make their way to a military hospital to take part in a risky surgery. Andrew wants everybody to know about his relationship with Maggie.
There is plenty of turmoil after Richard messes with the staff pairings. Arizona takes a risk to help a woman who is pregnant with quadruplets.
Jackson learns about April's pregnancy. Alex and the doctors need to deal with a triple organ transplant surgery.
Meredith wishes that she had not taken a step forward with Will. Maggie feels disconnected whilst Amelia thinks about her relationship with Owen.